Effect of Metformin on cognitive behaviour and re-purposing as a treatment for
Alzheimer's Disease 


   Note: An Official Proposal has not been Submitted to NACC.


   Lead Investigator:    Lisa Morris
   Institution      :    The Open University
   E-Mail           :    lisa410@hotmail.co.uk
   Proposal ID      :    1740



   Proposal Description:
   The purpose of the this project is to test the hypothesis that there will be a difference in cognitive test results between a treatment group (Metformin administered) and a control group (Placebo administered). This initial data request will provide some primary data for the analysis of the investigation and will be included in a statistical test to determine if there is a significant difference between the two groups. The outcome I will be looking for is to determine the mechanisms of metformin and its effects on slowing cognitive decline and to conclude if there is further research to be carried out for Metformin to become a repurposed drug for Alzheimer's Disease.